Tangletongue is one of the most sought-after Uniques in Path of Exile 2, a game that continues to evolve with each public test and developer reveal. Known for its powerful synergy with poison, chaos damage, and ailment-based builds, Tangletongue isn't just a weapon—it's a build enabler.In this guide, we'll explore everything you need to know about Tangletongue, including:

What Tangletongue is

Its stats and effects

How to obtain it (drops, farming methods, and boss strategies)

Ideal builds and classes

How to scale and craft around it

Farming strategies for solo and group play

Alternatives if you can't get one

What is Tangletongue in Path of Exile 2?

Tangletongue is a unique Dagger in Path of Exile 2, designed for characters who specialize in poison, ailment proliferation, and damage-over-time effects. This weapon offers a potent combination of chaos damage bonuses, ailment enhancements, and utility stats that make it a go-to choice for builds like Poison Assassin, Venomous Shadowblade, or Chaos Spellblades.

Tangletongue Stats (Example Roll)

While the exact stats may vary slightly due to implicit tiers or balancing during seasons, a typical Tangletongue includes:

Base Weapon Type: Dagger

Damage: Moderate base physical, high added chaos

Implicit: +40% to Global Critical Strike Multiplier (common for Daggers)

Grants increased Poison Duration

+ to Level of Chaos Skills or Chaos DoT Multiplier

Chance to Poison on Hit

Enemies Poisoned by You take increased Chaos Damage

30-50% increased Damage over Time

Socketed Skills apply Poison

These features make it especially effective for builds that rely on spreading poison through multiple hits or area-of-effect chaos skills.

How to Get Tangletongue in Path of Exile 2

There are several ways to obtain Tangletongue, but none of them are guaranteed. Here's a breakdown of your best options:

1. Target Farming via Bosses (World Bosses and Dungeon Lords)

In Path of Exile 2, target farming Unique drops is more viable than ever, especially thanks to the reworked Boss Loot Tables. Tangletongue has been reported to drop from:

The Blightheart Broodqueen

Found in Rotting Garden Dungeon (Act 5 or Act 7, depending on branching questlines)

This corrupted chaos-themed boss has a chance to drop several poison-themed Uniques.

Use Corruption Keys to access her altar version for improved drop rates.

Sable Horror Primeval

Located deep in the Chasm of Decay, this world boss spawns weekly on rotation and may drop Tangletongue from its Abyss Cache chest.

Tip: Stack Increased Chaos Drop Chance modifiers on your gear, and use party aura buffs to boost your chance if you're running with friends.

2. Ritual and Warbands Leagues (League-specific Drops)

Certain Uniques like Tangletongue are league-locked or have a significantly higher drop rate when playing Ritual or Warbands mechanics, which return in Path of Exile 2 through shrines and echoes.

Activate Ritual Altars and focus on Chaos-themed maps (Swamp, Blightwoods).

Prioritize monsters with “Poisonous,” “Toxic,” or “Abyssal” mods for better synergy with Tangletongue's loot table.

Sacrifice excess gear in the Ritual reward pool to “reroll” item offerings, increasing chances of Uniques appearing.

3. Chaos Crucible Farming

The Chaos Crucible is a new endgame mechanic in Path of Exile 2, somewhat similar to Delirium in PoE1. This corrupted area features:

Continuous waves of chaos-infused monsters

Chance to drop Toxic Reliquary Keys

Final bosses that can drop Tangletongue, especially on Tier 2+ Crucibles

Make sure to:

Use chaos resistance gear (capped at 75% or more)

Equip AoE poison-clearing skills

Focus on clear speed + high poison uptime

4. Divination Cards or Item Sets (if Available)

While no specific Divination Card set for Tangletongue has been officially confirmed in Path of Exile 2 as of this writing, it's worth keeping an eye out in patch notes and Reddit discoveries.

If implemented, cards such as:

"The Toxic Blade"

"Venom's Gift"

Or “Whispering Fang” (speculative)

…could be tied to acquiring this dagger.

5. Trade and Crafting via Rune Combination or Essence Transmutation

In Path of Exile 2's crafting system, Runes and Essences play a pivotal role. While Tangletongue cannot be directly crafted, you can:

Use Runes of Chaos, Runes of Ailment Proliferation, and Runes of Decay on high-tier Daggers to mimic Tangletongue's core stats

Use Tainted Blessings (rare Chaos altar drops) to attempt Unique conversions

If you're playing on Trade-enabled servers, monitor the Chaos-Dagger listings or use advanced filters for “Enemies Poisoned Take Increased Chaos Damage.”

Best Builds That Use Tangletongue

1. Poison Assassin

Class: Shadow

Skill Core: Poisoned Daggers, Venom Trap, Deadly Dash

Pros: Massive scaling through ailment multipliers and crit

2. Venomous Witch (Chaos Spellblade)

Class: Witch

Skills: Toxic POE 2 Orbs, Withering Pulse, Curse of Decay

Focus: Chaos DoT stacking with energy shield defenses

3. Ranger – Toxic Shot + Mirage Arrow Hybrid

Skills: Toxic Shot, Poison Arrow Trap, Frenzy

Tangletongue offers poison chance + chaos scaling without sacrificing bow nodes

How to Scale Tangletongue Effectively

To get the most out of Tangletongue:

Stack Poison Duration (e.g. from passives and gear)

Scale Chaos Damage Over Time Multiplier

Boost Chance to Poison on Hit (up to 100%)

Use support gems like:

Unbound Ailments

Vile Toxins

Deadly Ailments

Passive Tree Tips:

Take nodes in the Shadow, Ranger, and Witch starting areas

Keystone: Perfect Agony (lets crit multiplier affect poison damage)

Jewel: Growing Agony, Spreading Rot

Tangletongue Farming Tips (Solo and Group)

Solo Play

Focus on Chaos Crucible farming

Stack chaos resist and flask uptime

Use Loot Filters that highlight “Poison” and “Chaos” keywords

Group Play

Designate one player to run quantity/rarity gear

Use Ailment Support Auras to boost poison uptime

Group farm in Ritual maps with Shrine Modifiers

Alternatives to Tangletongue

If you're unable to find Tangletongue, consider:

Widowfang – a Dagger with less duration scaling but high raw DoT

The Scorpion's Tail – new claw with built-in poison leech

Rare Crafted Daggers with:

“+Chaos DoT Multiplier”

“Chance to Poison”

“Socketed Skills apply Poison”

Final Thoughts

Tangletongue is a cornerstone item in the poison/chaos meta of Path of Exile 2, and while it's not the easiest Unique to obtain, the variety of ways to target-farm or craft around it makes it accessible to dedicated players. Whether you're soloing Chaos Crucibles, running Rituals,POE2 Currency or taking on endgame bosses, the dagger is well worth the grind.

If you're building a poison or chaos DoT archetype in Path of Exile 2, Tangletongue isn't just a weapon—it's a gateway to top-tier DPS potential.